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Etizolam is a synthetic benzodiazepine with pharmacological effects resembling those of the model drug, benzodiazepine diazepam.
It originated in Japan and is currently restricted for use as a medication in Japan, Italy, and India.
Its primary application involves treating generalized anxiety disorder, which has depressive symptoms.
Etizolam (0.5 mg twice daily) has a comparable therapeutic effect in this disorder to that of Alprazolam (0.5 mg twice daily) and bromazepam (3 mg twice daily). Etizolam seems to have minor effects on cognitive functioning when taken at the recommended dose of 0.5 mg twice daily.