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A prescription opioid analgesic medication called codeine is used to treat mild to moderate pain.

Evidence does not support its use in the prevention of acute cough in children or adults. It is not advised as a cough treatment in Europe for people younger than 12 years old. It is often taken orally. Usually, it begins to function after 45 minutes, reaching its peak effectiveness after two hours. The effects last for around four to five hours.